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Predefinição
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PBB/25942
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Predefinição:PBB
SIN3A
PDB
1g1e.
Estruturas disponíveis
PDB
Busca de ortólogos:
PDBe
,
RCSB
Lista de códigos PDB
1PO4
Identificadores
Símbolos
SIN3A
; DKFZp434K2235; FLJ90319; KIAA0700
IDs externos
OMIM:
607776
MGI
:
107157
HomoloGene
:
32124
GeneCards
:
SIN3A Gene
Ontologia do gene
Função molecular
•
RNA polymerase II activating transcription factor binding
•
RNA polymerase II repressing transcription factor binding
•
RNA polymerase II transcription corepressor activity
•
DNA binding
•
chromatin binding
•
sequence-specific DNA binding transcription factor activity
•
transcription corepressor activity
•
protein binding
•
protein complex binding
•
protein deacetylase activity
Componente celular
•
kinetochore
•
nucleus
•
nucleoplasm
•
transcription factor complex
•
nucleolus
•
Sin3 complex
•
transcriptional repressor complex
Processo biológico
•
negative regulation of transcription from RNA polymerase II promoter
•
in utero embryonic development
•
activation of innate immune response
•
positive regulation of defense response to virus by host
•
DNA replication
•
protein deacetylation
•
aging
•
blood coagulation
•
response to organic nitrogen
•
positive regulation of chromatin silencing
•
cellular protein localization
•
negative regulation of apoptotic process
•
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
•
cellular lipid metabolic process
•
small molecule metabolic process
•
negative regulation of transcription, DNA-dependent
•
positive regulation of transcription from RNA polymerase II promoter
•
interphase of mitotic cell cycle
•
response to methylglyoxal
•
cellular response to glucose stimulus
•
negative regulation of protein localization to nucleus
•
negative regulation of histone H3-K27 acetylation
•
negative regulation of transcription regulatory region DNA binding
Sources:
Amigo
/
QuickGO
Ortólogos
Espécies
Humano
Rato
Entrez
25942
20466
Ensembl
ENSG00000169375
ENSMUSG00000042557
UniProt
Q96ST3
Q60520
RefSeq (mRNA)
NM_001145357
NM_001110350
RefSeq (proteína)
NP_001138829
NP_001103820
Localização (UCSC)
Chr 15:
75.66 – 75.75 Mb
Chr 9:
57.07 – 57.13 Mb
Busca
PubMed
[1]
[2]
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