CRISP3

CRISP3
Identificadores
Nomes alternativos	CRISP3
IDs externos	OMIM: 618062 HomoloGene: 136801 GeneCards: CRISP3
Ontologia genética
Função molecular	• função molecular;
Componente celular	• specific granule; • Exossoma; • extracellular region; • extracellular space; • specific granule lumen; • tertiary granule lumen; • GO:0005578 matriz extracelular; • membrane; • integral component of membrane;
Processo biológico	• defense response; • sistema imune inato; • neutrophil degranulation;
	Sources:Amigo / QuickGO
Padrão de expressão RNA
	Mais dados de referência de expressão
Ortólogos
	10321
	n/a
	ENSG00000096006
	n/a
	P54108
	n/a
	NM_006061; NM_001190986; NM_001368123
	n/a
	NP_001177915; NP_006052; NP_001355052
	n/a
	Wikidata
Ver/Editar Humano

A proteína secretora rica em cisteína 3 é uma proteína secretora rica em cisteína que em humanos é codificada pelo gene CRISP3.^[2]^[3]^[4]

Referências

↑ «Human PubMed Reference:»
↑ Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD (agosto de 1996). «The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3». Eur J Biochem. 236 (3): 827–36. PMID 8665901. doi:10.1111/j.1432-1033.1996.t01-1-00827.x
↑ Udby L, Calafat J, Sorensen OE, Borregaard N, Kjeldsen L (setembro de 2002). «Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils». J Leukoc Biol. 72 (3): 462–9. PMID 12223513
↑ «Entrez Gene: CRISP3 cysteine-rich secretory protein 3»

Leitura adicional editar

Maruyama K, Sugano S (1994). «Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.». Gene. 138 (1-2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8
Kjeldsen L, Cowland JB, Johnsen AH, Borregaard N (1996). «SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein.». FEBS Lett. 380 (3): 246–50. PMID 8601434. doi:10.1016/0014-5793(96)00030-0
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). «Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.». Gene. 200 (1-2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3
Cowland JB, Borregaard N (2000). «The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules.». J. Leukoc. Biol. 66 (6): 989–95. PMID 10614782
Friess H, Ding J, Kleeff J, et al. (2002). «Identification of disease-specific genes in chronic pancreatitis using DNA array technology.». Ann. Surg. 234 (6): 769–78; discussion 778–9. PMC 1422136 . PMID 11729383. doi:10.1097/00000658-200112000-00008
Udby L, Cowland JB, Johnsen AH, et al. (2002). «An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions.». J. Immunol. Methods. 263 (1-2): 43–55. PMID 12009203. doi:10.1016/S0022-1759(02)00033-9
Kosari F, Asmann YW, Cheville JC, Vasmatzis G (2003). «Cysteine-rich secretory protein-3: a potential biomarker for prostate cancer.». Cancer Epidemiol. Biomarkers Prev. 11 (11): 1419–26. PMID 12433721
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899
Liao Q, Kleeff J, Xiao Y, et al. (2003). «Preferential expression of cystein-rich secretory protein-3 (CRISP-3) in chronic pancreatitis.». Histol. Histopathol. 18 (2): 425–33. PMID 12647793
Mungall AJ, Palmer SA, Sims SK, et al. (2003). «The DNA sequence and analysis of human chromosome 6.». Nature. 425 (6960): 805–11. PMID 14574404. doi:10.1038/nature02055
Udby L, Sørensen OE, Pass J, et al. (2004). «Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma.». Biochemistry. 43 (40): 12877–86. PMID 15461460. doi:10.1021/bi048823e
Gerhard DS, Wagner L, Feingold EA, et al. (2004). «The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).». Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504
Udby L, Bjartell A, Malm J, et al. (2005). «Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract.». J. Androl. 26 (3): 333–42. PMID 15867000. doi:10.2164/jandrol.04132
Udby L, Lundwall A, Johnsen AH, et al. (2005). «beta-Microseminoprotein binds CRISP-3 in human seminal plasma.». Biochem. Biophys. Res. Commun. 333 (2): 555–61. PMC 1939934 . PMID 15950934. doi:10.1016/j.bbrc.2005.05.139
Bjartell A, Johansson R, Björk T, et al. (2006). «Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland.». Prostate. 66 (6): 591–603. PMID 16388501. doi:10.1002/pros.20342
Bjartell AS, Al-Ahmadie H, Serio AM, et al. (2007). «Association of cysteine-rich secretory protein 3 and beta-microseminoprotein with outcome after radical prostatectomy.». Clin. Cancer Res. 13 (14): 4130–8. PMC 2660867 . PMID 17634540. doi:10.1158/1078-0432.CCR-06-3031
Laine M, Porola P, Udby L, et al. (2007). «Low salivary dehydroepiandrosterone and androgen-regulated cysteine-rich secretory protein 3 levels in Sjögren's syndrome.». Arthritis Rheum. 56 (8): 2575–84. PMID 17665393. doi:10.1002/art.22828

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[1] «Human PubMed Reference:»

[pmid8665901-2] Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD (agosto de 1996). «The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3». Eur J Biochem. 236 (3): 827–36. PMID 8665901. doi:10.1111/j.1432-1033.1996.t01-1-00827.x

[pmid12223513-3] Udby L, Calafat J, Sorensen OE, Borregaard N, Kjeldsen L (setembro de 2002). «Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils». J Leukoc Biol. 72 (3): 462–9. PMID 12223513

[entrez-4] «Entrez Gene: CRISP3 cysteine-rich secretory protein 3»

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[3]

[4]

[1]