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Predefinição
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PBB/359
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Predefinição:PBB
Aquaporina 2 (ductos colectores)
Estruturas disponíveis
PDB
Busca de ortólogos:
PDBe
,
RCSB
Lista de códigos PDB
4NEF
,
4OJ2
Identificadores
Símbolos
AQP2
; AQP-CD; WCH-CD
IDs externos
OMIM:
107777
MGI
:
1096865
HomoloGene
:
20137
IUPHAR
:
AQP2
GeneCards
:
AQP2 Gene
Ontologia do gene
Função molecular
•
actin binding
•
water transmembrane transporter activity
•
glycerol transmembrane transporter activity
•
water channel activity
•
PDZ domain binding
Componente celular
•
lysosome
•
early endosome
•
rough endoplasmic reticulum
•
trans-Golgi network
•
plasma membrane
•
membrane
•
integral component of membrane
•
basolateral plasma membrane
•
apical plasma membrane
•
clathrin-coated vesicle
•
transport vesicle membrane
•
protein complex
•
recycling endosome
•
extracellular vesicular exosome
•
exocytic vesicle
Processo biológico
•
renal water transport
•
water transport
•
cell volume homeostasis
•
apoptotic process
•
hyperosmotic response
•
female pregnancy
•
aging
•
excretion
•
response to salt stress
•
response to lithium ion
•
glycerol transport
•
actin filament depolymerization
•
response to lipopolysaccharide
•
response to glucagon
•
response to starvation
•
cellular response to water deprivation
•
response to calcium ion
•
positive regulation of calcium ion transport
•
transmembrane transport
•
cellular response to copper ion
•
cellular response to mercury ion
•
metanephric collecting duct development
Sources:
Amigo
/
QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies
Humano
Rato
Entrez
359
11827
Ensembl
ENSG00000167580
ENSMUSG00000023013
UniProt
P41181
P56402
RefSeq (mRNA)
NM_000486
NM_009699
RefSeq (proteína)
NP_000477
NP_033829
Localização (UCSC)
Chr 12:
50.34 – 50.35 Mb
Chr 15:
99.58 – 99.58 Mb
Busca
PubMed
[1]
[2]
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