Lipase pancreática
Cartoon diagram of human pancreatic lipase (colored by secondary structure: alpha helices in red, beta sheets in yellow, and random coil in green) in complex with pig colipase (colored blue) and a small molecule inhibitor (upper left).[1]
Estruturas disponíveis
PDB Busca de ortólogos: PDBe, RCSB
Identificadores
Símbolos PNLIP; PL; PNLIPD; PTL
IDs externos OMIM: 246600 MGI97722 HomoloGene30999 ChEMBL: 1812 GeneCards: PNLIP Gene
Número EC 3.1.1.3
Ortólogos
Espécies Humano Rato
Entrez 5406 69060
Ensembl ENSG00000175535 ENSMUSG00000046008
UniProt P16233 Q6P8U6
RefSeq (mRNA) NM_000936 NM_026925
RefSeq (proteína) NP_000927 NP_081201
Localização (UCSC) Chr 10:
118.31 – 118.33 Mb
Chr 19:
58.67 – 58.68 Mb
Busca PubMed [1] [2]

Referências

  1. PDB 1LPB; Egloff MP, Marguet F, Buono G, Verger R, Cambillau C, van Tilbeurgh H (março de 1995). «The 2.46 Å resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate». Biochemistry. 34 (9): 2751–62. PMID 7893686. doi:10.1021/bi00009a003