Início
Aleatório
Aqui perto
Entrar
Definições
Donativos
Sobre a Wikipédia
Avisos gerais
Pesquisar
Predefinição
:
PBB/79068
Língua
Vigiar
Editar
<
Predefinição:PBB
Fat mass and obesity associated
Estruturas disponíveis
PDB
Busca de ortólogos:
PDBe
,
RCSB
Lista de códigos PDB
3LFM
Identificadores
Símbolos
FTO
; KIAA1752; MGC5149
IDs externos
OMIM:
610966
MGI
:
1347093
HomoloGene
:
8053
GeneCards
:
FTO Gene
Número EC
1.14.11.-
Ontologia do gene
Função molecular
•
ferrous iron binding
•
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
•
oxidative RNA demethylase activity
•
oxidative DNA demethylase activity
•
DNA-N1-methyladenine dioxygenase activity
Componente celular
•
núcleo
Processo biológico
•
temperature homeostasis
•
DNA dealkylation involved in DNA repair
•
regulation of lipid storage
•
oxidative single-stranded DNA demethylation
•
oxidative single-stranded RNA demethylation
•
regulation of multicellular organism growth
•
RNA repair
•
regulation of respiratory system process
•
adipose tissue development
•
regulation of white fat cell proliferation
•
oxidative demethylation
•
DNA demethylation
Sources:
Amigo
/
QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies
Humano
Rato
Entrez
79068
26383
Ensembl
ENSG00000140718
ENSMUSG00000055932
UniProt
Q9C0B1
Q8BGW1
RefSeq (mRNA)
NM_001080432.2
NM_011936.2
RefSeq (proteína)
NP_001073901.1
NP_036066.2
Localização (UCSC)
Chr 16:
53.74 – 54.16 Mb
Chr 8:
91.31 – 91.67 Mb
Busca
PubMed
[1]
[2]
v
d
e