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Predefinição
:
PBB/796
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Predefinição:PBB
Produtora de calcitonine
Estruturas disponíveis
PDB
Busca de ortólogos:
PDBe
,
RCSB
Lista de códigos PDB
2JXZ
Identificadores
Símbolos
CALCA
; CALC1; CGRP; CGRP-I; CGRP1; CT; KC
IDs externos
OMIM:
114130
MGI
:
2151253
HomoloGene
:
105263
ChEMBL
:
5293
GeneCards
:
CALCA Gene
Ontologia do gene
Função molecular
•
receptor binding
•
hormone activity
•
protein binding
•
calcitonin receptor binding
•
protein complex binding
Componente celular
•
região extracelular
•
extracellular space
•
núcleo
•
citoplasma
•
neuronal cell body
•
terminal button
Processo biológico
•
endothelial cell proliferation
•
vasculature development
•
neurological system process involved in regulation of systemic arterial blood pressure
•
vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
•
regulation of heart rate
•
G-protein coupled receptor internalization
•
monocyte chemotaxis
•
protein phosphorylation
•
resposta inflamatória
•
leukocyte cell-cell adhesion
•
adenylate cyclase-activating G-protein coupled receptor signaling pathway
•
activation of adenylate cyclase activity
•
elevação da concentração iónica do cálcio citosólico
•
neuropeptide signaling pathway
•
sinalização célula-célula
•
embryo kkkkkkkkkkon
•
aging
•
feeding behavior
•
regulation of blood pressure
•
response to heat
•
negative regulation of calcium ion transport into cytosol
•
negative regulation of ossification
•
positive regulation of cAMP biosynthetic process
•
receptor internalization
•
negative regulation of neurological system process
•
activation of protein kinase activity
•
positive regulation of interleukin-1 alpha production
•
positive regulation of interleukin-8 production
•
vasodilation
•
endothelial cell migration
•
positive regulation of macrophage differentiation
•
negative regulation of osteoclast differentiation
•
positive regulation of adenylate cyclase activity
•
negative regulation of blood pressure
•
positive regulation of ossification
•
negative regulation of bone resorption
•
negative regulation of transcription, DNA-dependent
•
positive regulation of vasodilation
•
negative regulation of smooth muscle contraction
•
response to pain
•
regulation of inflammatory response
•
detection of temperature stimulus involved in sensory perception of pain
•
cytosolic calcium ion homeostasis
•
elevação da concentração iónica do cálcio citosólico involved in phospholipase C-activating G-protein coupled signaling pathway
Sources:
Amigo
/
QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies
Humano
Rato
Entrez
796
12310
Ensembl
ENSG00000110680
ENSMUSG00000030669
UniProt
P01258
P70160
RefSeq (mRNA)
NM_001033952.2
NM_001033954.3
RefSeq (proteína)
NP_001029124.1
NP_001029126.1
Localização (UCSC)
Chr 11:
14.99 – 14.99 Mb
Chr 7:
114.63 – 114.64 Mb
Busca
PubMed
[1]
[2]
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