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Predefinição
:
PBB/929
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Predefinição:PBB
Molécula CD14
Renderização baseada em
PDB
1WWL
.
Estruturas disponíveis
PDB
Busca de ortólogos:
PDBe
,
RCSB
Lista de códigos PDB
4GLP
Identificadores
Símbolo
CD14
IDs externos
OMIM:
158120
MGI
:
88318
HomoloGene
:
493
GeneCards
:
CD14 Gene
Ontologia do gene
Função molecular
•
lipopolysaccharide binding
•
opsonin receptor activity
•
peptidoglycan receptor activity
•
lipoteichoic acid binding
Componente celular
•
extracellular region
•
extracellular space
•
plasma membrane
•
cell surface
•
endosome membrane
•
anchored to membrane
•
membrane raft
Processo biológico
•
toll-like receptor signaling pathway
•
MyD88-dependent toll-like receptor signaling pathway
•
MyD88-independent toll-like receptor signaling pathway
•
phagocytosis
•
apoptotic process
•
inflammatory response
•
cell surface receptor signaling pathway
•
I-kappaB kinase/NF-kappaB cascade
•
response to heat
•
positive regulation of tumor necrosis factor production
•
toll-like receptor 2 signaling pathway
•
toll-like receptor 3 signaling pathway
•
toll-like receptor 4 signaling pathway
•
TRIF-dependent toll-like receptor signaling pathway
•
toll-like receptor TLR1:TLR2 signaling pathway
•
toll-like receptor TLR6:TLR2 signaling pathway
•
innate immune response
•
positive regulation of endocytosis
•
positive regulation of cytokine secretion
•
cellular response to lipopolysaccharide
•
cellular response to lipoteichoic acid
Sources:
Amigo
/
QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies
Humano
Rato
Entrez
929
12475
Ensembl
ENSG00000170458
ENSMUSG00000051439
UniProt
P08571
P10810
RefSeq (mRNA)
NM_000591
NM_009841
RefSeq (proteína)
NP_000582
NP_033971
Localização (UCSC)
Chr 5:
140.01 – 140.01 Mb
Chr 18:
36.73 – 36.73 Mb
Busca
PubMed
[1]
[2]
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