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Predefinição
:
PBB/959
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Predefinição:PBB
CD154
Renderização com base em
PDB
1aly.
Estruturas disponíveis
PDB
Busca de ortólogos:
PDBe
,
RCSB
Lista de códigos PDB
1ALY
,
1I9R
,
3LKJ
,
3QD6
Identificadores
Símbolos
CD40LG
; CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L
IDs externos
OMIM:
300386
MGI
:
88337
HomoloGene
:
56
GeneCards
:
CD40LG Gene
Ontologia do gene
Função molecular
•
cytokine activity
•
tumor necrosis factor receptor binding
•
CD40 receptor binding
Componente celular
•
extracellular space
•
membrana plasmática
•
integral to plasma membrane
•
external side of plasma membrane
•
integral to membrane
Processo biológico
•
positive regulation of immune response to tumor cell
•
anti-apoptosis
•
resposta inflamatória
•
leukocyte cell-cell adhesion
•
platelet activation
•
B cell differentiation
•
positive regulation of B cell proliferation
•
positive regulation of interferon-gamma production
•
positive regulation of interleukin-10 production
•
positive regulation of interleukin-12 production
•
B cell proliferation
•
isotype switching
•
positive regulation of MHC class II biosynthetic process
•
immunoglobulin secretion
•
regulation of immune response
•
regulation of immunoglobulin secretion
•
positive regulation of endothelial cell apoptotic process
Sources:
Amigo
/
QuickGO
Padrões de expressão do ARN
Mais dados de expressão
Ortólogos
Espécies
Humano
Rato
Entrez
959
21947
Ensembl
ENSG00000102245
ENSMUSG00000031132
UniProt
P29965
P27548
RefSeq (mRNA)
NM_000074.2
NM_011616.2
RefSeq (proteína)
NP_000065.1
NP_035746.2
Localização (UCSC)
Chr X:
135.73 – 135.74 Mb
Chr X:
57.21 – 57.22 Mb
Busca
PubMed
[1]
[2]
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