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|legenda =
|nome_nativo =
|data_nascimento ={{dni|lang=br|27|4|1903|si}}
|local_nascimento =[[Berlim]]
|data_morte ={{nowrap|{{morte|lang=br|26|10|1996|27|4|1903}}}}
|local_morte =[[Aberdeen (Escócia)]]
|causa_morte =
|conhecido_por =
|influenciado =
|premio ={{nowrap|[[Medalha Real]] (1979)}}, {{nowrap|[[Prémio Harvey|Prêmio Harvey]] (1981)}}, {{nowrap|[[]] (1982)}}
|conjuge =
|religiao =
|notas =
}}
'''Hans Walter Kosterlitz''' [[Membro da Royal Society|FRS]]<ref>{{Link|en|2=http://rsbm.royalsocietypublishing.org/content/early/2013/04/04/rsbm.2012.0037|3=Biographical Memoirs of Fellows of the Royal Society}}</ref> ([[Berlim]], {{dtlink|lang=br|27|4|1903}} — [[Aberdeen (Escócia)]], {{dtlink|lang=br|26|10|1996}}) foi um [[Biologia|biólogo]] [[Reino Unido|britânico]] nascido na [[Alemanha]].
{{Tradução de||en|Hans Kosterlitz}}
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was a [[Germany|German]]-born [[Great Britain|British]] biologist, who graduated [[Doctor of Medicine#Equivalent degrees in other countries|Doctor of Medicine (Dr. med)]] in [[Berlin]]. He settled in [[Scotland]] and took a [[Doctor of Science]] (DSc) at the [[University of Aberdeen]] where he was, for many years, [[Reader (academic rank)|Reader]] in [[Physiology]].<ref>{{Cite doi|10.1139/cjpp-76-3-244}}</ref><ref>{{Cite pmid|8945465}}</ref>
Kosterlitz is best known for his work on [[endorphin]]s.<ref>{{Cite pmid|9142421}}</ref><ref>{{cite pmid|9142417}}</ref> He performed a famous [[experiment]] that he envisioned in a dream while sleeping. He stimulated a strip of [[guinea pig]] [[intestine]] electrically and was able to record the [[Muscle contraction|contraction]]s with a [[polygraph]]. He then found that if you added [[opiate]]s to the solution, the intestine would not contract. Opiates inhibit intestinal contraction. Those contractions were later found to resume in the presence of both opiates and an [[antagonist]] such as [[naloxone]]. Later, [[endogenous]] endorphins were discovered by applying [[tissue (biology)|tissue]] (pig brain [[Homogenization (biology)|cell homegenate]]) to the apparatus. This caused the contractions to cease. The degree to which an opiate [[agonist]] inhibits contractions in the guinea pig [[ileum]] is highly [[correlation|correlated]] to its [[potency (pharmacology)|potency]]. Kosterlitz shared the Albert [[Lasker Award]] with John Hughes and Solomon Snyder in 1978 for his work in the discovery of the opiate receptors and their natural ligands.
The University of Aberdeen officially opens its new Kosterlitz Centre on the 16th September 2010 in memory of Professor Hans Kosterlitz, who joined the University in 1933.
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{{Referências}}
{{Medalha Real (1951 — 2000)}}
{{Esboço-bioquímico}}
{{Controle de autoridade}}
{{DEFAULTSORT:Kosterlitz, Hans Walter}}
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