Quinolinato sintase

Quinolinato sintase (EC 2.5.1.72, NadA, QS, quinolinate synthetase) é uma enzima com nome sistemáticos glycerone phosphate:iminosuccinate alkyltransferase (cyclizing).^[1]^[2]^[3]^[4]^[5]

Referências

↑ Ollagnier-de Choudens, S.; Loiseau, L.; Sanakis, Y.; Barras, F.; Fontecave, M. (2005). «Quinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis». FEBS Lett. 579 (17): 3737–3743. PMID 15967443. doi:10.1016/j.febslet.2005.05.065
↑ Katoh, A.; Uenohara, K.; Akita, M.; Hashimoto, T. (2006). «Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid». Plant Physiol. 141 (3): 851–857. PMC 1489895 . PMID 16698895. doi:10.1104/pp.106.081091
↑ Sakuraba, H.; Tsuge, H.; Yoneda, K.; Katunuma, N.; Ohshima, T. (2005). «Crystal structure of the NAD biosynthetic enzyme quinolinate synthase». J. Biol. Chem. 280 (29): 26645–26648. PMID 15937336. doi:10.1074/jbc.C500192200
↑ Rousset, C.; Fontecave, M.; Ollagnier de Choudens, S. (2008). «The [4Fe-4S] cluster of quinolinate synthase from Escherichia coli: Investigation of cluster ligands». FEBS Lett. 582 (19): 2937–2944. PMID 18674537. doi:10.1016/j.febslet.2008.07.032
↑ Saunders, A.H.; Booker, S.J. (2008). «Regulation of the activity of Escherichia coli quinolinate synthase by reversible disulfide-bond formation». Biochemistry. 47 (33): 8467–8469. PMC 3319134 . PMID 18651751. doi:10.1021/bi801135y

[1] Ollagnier-de Choudens, S.; Loiseau, L.; Sanakis, Y.; Barras, F.; Fontecave, M. (2005). «Quinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis». FEBS Lett. 579 (17): 3737–3743. PMID 15967443. doi:10.1016/j.febslet.2005.05.065

[2] Katoh, A.; Uenohara, K.; Akita, M.; Hashimoto, T. (2006). «Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid». Plant Physiol. 141 (3): 851–857. PMC 1489895 . PMID 16698895. doi:10.1104/pp.106.081091

[3] Sakuraba, H.; Tsuge, H.; Yoneda, K.; Katunuma, N.; Ohshima, T. (2005). «Crystal structure of the NAD biosynthetic enzyme quinolinate synthase». J. Biol. Chem. 280 (29): 26645–26648. PMID 15937336. doi:10.1074/jbc.C500192200

[4] Rousset, C.; Fontecave, M.; Ollagnier de Choudens, S. (2008). «The [4Fe-4S] cluster of quinolinate synthase from Escherichia coli: Investigation of cluster ligands». FEBS Lett. 582 (19): 2937–2944. PMID 18674537. doi:10.1016/j.febslet.2008.07.032

[5] Saunders, A.H.; Booker, S.J. (2008). «Regulation of the activity of Escherichia coli quinolinate synthase by reversible disulfide-bond formation». Biochemistry. 47 (33): 8467–8469. PMC 3319134 . PMID 18651751. doi:10.1021/bi801135y

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