Ciclo-oxigenase-1 (COX-1) também conhecida como prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 ou prostaglandin H2 synthase 1 é uma enzima que em humanos é codificada pelo gene PTGS1. É responsável pela catálise de prostaglandinas e tromboxano. Possui função fisiológica constitutiva e participa de uma série de processos de manutenção dos processos do organismo como a proteção da mucosa gástrica, hemostasia e regulação de perfusão renal.[1]

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Notas e referências

  1. SCHELLACK, Gustav. Farmacologia na prática clínica da área de saúde. São Paulo: Fundamento Educacional, 2006

Leitura de apoio editar

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